APPROACH FOR ENHANCING THE RELIABILITY OF SOFTWARE

Reliability is always important in all systems but sometimes it is more important than other quality attributes, especially inmission critical systems where the severity of consequence resulting from failure is very high. Software reliabilityengineering is focused on comprehensive techniques for developing reliable software and for proper assessment andimprovement of reliability. Reliability metrics, models and measurements form an essential part of software reliabilityengineering process. Appropriate metrics, models and measurement techniques should be applied to produce reliablesoftware. Hence, it is the intention to develop some approaches to enhance the reliability of software by the analysis of thestructure of the software, execution scenario for various inputs and operational profile.Keywords: Software Reliability, Rate of occurrence of failure (ROCOF), Mean Time to Failure (MTTF),Hardware Reliability, Mean Time between Failure (MTBR)

Cocaine Cardiac Toxicity: Revisited

Cocaine is a potent stimulant which affects cardiovascular system severely. The mechanism of cardiac toxicity depends on multiple factors. Cocaine increases sympathetic stimulation and causes excess catecholamine secretion. Besides, its indirect sympathomimetic effect also directly exerts cardiotoxic effect by different cellular, molecular, and ionic mechanisms, resulting in acute or chronic cardiovascular impairment. Cardiac arrhythmia and acute myocardial ischemia or infarction is the most common cause of cocaine-induced sudden cardiac death. Chronic cocaine abuse can develop sustained hypertension or myocarditis or cardiomyopathy leading to depressed left ventricular function. Therapy for cocaine induced cardiac toxicity generally includes use of benzodiazepine agents, nitric oxide mediated vasodilators, alpha blockers and even calcium channel blockers. Beta blockers are relatively contraindicated in acute settings of cocaine cardiovascular toxicity. Hypersensitivity reaction to cocaine is often manifested by infiltration of eosinophilic or mononuclear cells without myocardial cell damage. Vascular dissection, endocarditis, and tricuspid valvular abnormalities are some less frequent manifestations in cocaine-induced cardiac toxicity

Mapping of the multifoliate pinna (mfp) leaf-blade morphology mutation in grain pea Pisum sativum

The multifoliate pinna (mfp) mutation alters the leaf-blade architecture of pea, such that simple tendril pinnae of distal domain are replaced by compound pinna blades of tendrilled leaflets in mfp homozygotes. The MFP locus was mapped with reference to DNA markers using F2 and F2:5 RIL as mapping populations. Among 205 RAPD, 27 ISSR and 35 SSR markers that demonstrated polymorphism between the parents of mapping populations, three RAPD markers were found linked to the MFP locus by bulk segregant analyses on mfp/mfp and MFP/MFP bulks assembled from the F2:5 population. The segregational analysis of mfp and 267 DNA markers on 96 F2 plants allowed placement of 26 DNA markers with reference to MFP on a linkage group. The existence of common markers on reference genetic maps and MFP linkage group developed here showed that MFP is located on linkage group IV of the consensus genetic map of pea

Development and validation of UV Spectrophotometric method for simultaneous estimation of Lamivudine and Tenofovir Disproxil Fumarate in the combined dosage form

A Simple, precise, accurate and economical spectrophotometric method was developed and validated for simultaneous estimation of Lamivudine (LAM) and Tenofovir disoproxil fumarate (TDF) in combined  dosage form. In simultaneous equation method, LAM and TDF were quantified using their absorptivity values at selected wavelengths, viz., 276nm and 260nm respectively in water solvent system. LAM and TDF obeyed Beer’s law in the concentration range of 5-25μg/ml. Different analytical parameters such as linearity, precision, accuracy, limit of detection (LOD) and limit of quantification (LOQ) were determined as per ICH guidelines (Q2A & Q2B). % Recovery for both the drugs were in the range of 98.31-98.94%  indicating excellent accuracy. The methods were precise, with a relative standard deviation of less than 2% for both drugs. The simultaneous equation method permits simple, rapid and direct determination of LAM and TDF in commercially available combined dosage form without previous separations and can therefore be used for routine analysis. Keywords: Lamivudine, Tenofovir disoproxil fumarate, Spectrophotometric analysis, Simultaneous equation method

A Frequency Tunable Dielectric Resonator Antenna with Reduction of Cross Polarisation for Wi MAX and Sub 6 GHz 5G Applications

A frequency Tunable (mechanical tuning) Linearly Polarized (TLP) rectangular Dielectric Resonator Antenna(DRA) coupled with a horizontal/vertical-slot and excited with circular-ring type feed is investigated in this article.The frequency tunability (mechanical tuning) is achieved by the rotation of slot at different angles of the proposedstructure. Hence, two linearly polarized antennas have been proposed for different frequency bands such as Wi-MAX and Sub-6 GHz/5G, respectively, using slot variations (named as DRA-1 and DRA-2). TE 11δ mode has been excited in both the DRAs and confirmed by orientation of electric field inside the rectangular DRA. The measured -10 dB input impedance bandwidths of DRA-1 offer 21.60 % being centered at 2.87 GHz and the separation of co-polarized and cross-polarized field levels is above -24 dB in the broadside direction (xz-plane). Whereas DRA-2 offers measured -10 dB input impedance bandwidths of 23.03% being centered at 3.56 GHz having a separation of co-polarized and cross-polarized field levels are above -23 dB in the broadside direction (xz-plane). In addition, the proposed DRA-1 and DRA-2 show a maximum gain of 5.23 dBi and 4.75 dBi in broadside direction, respectively

A Novel Approach on Visual Question Answering by Parameter Prediction using Faster Region Based Convolutional Neural Network

Visual Question Answering (VQA) is a stimulating process in the field of Natural Language Processing (NLP) and Computer Vision (CV). In this process machine can find an answer to a natural language question which is related to an image. Question can be open-ended or multiple choice. Datasets of VQA contain mainly three components; questions, images and answers. Researchers overcome the VQA problem with deep learning based architecture that jointly combines both of two networks i.e. Convolution Neural Network (CNN) for visual (image) representation and Recurrent Neural Network (RNN) with Long Short Time Memory (LSTM) for textual (question) representation and trained the combined network end to end to generate the answer. Those models are able to answer the common and simple questions that are directly related to the image’s content. But different types of questions need different level of understanding to produce correct answers. To solve this problem, we use faster Region based-CNN (R-CNN) for extracting image features with an extra fully connected layer whose weights are dynamically obtained by LSTMs cell according to the question. We claim in this paper that a single R-CNN architecture can solve the problems related to VQA by modifying weights in the parameter prediction layer. Authors trained the network end to end by Stochastic Gradient Descent (SGD) using pretrained faster R-CNN and LSTM and tested it on benchmark datasets of VQA

Study of clinical outcome of acromioclavicular joint injury type III-VI treated by EndoButton and threads in adults

Background: Acromioclavicular joint dislocations are common in physically active young adults that too most common in persons who are participating in sports activities. Incidence is more in males who are participating in contact sports like rugby, basketball, hockey. It accounts for 9% of all shoulder injuries. Literature says the incidence is 3-4/1,00,000 population. The aim of the present study was to study the functional outcome of acromioclavicular joint after reconstruction of both acromioclavicular and coracoclavicular ligament using endo button system and to provide pain-free, mobile shoulder.Methods: In the present study, 15 patients were selected of age group 20-60 years. Acromioclavicular joint injuries are classified according to Rockwood classification and the findings from the physical examination and anteroposterior and axillary radiographs. All patients were treated as per status of injury level by either conservatively or operatively with open reduction and reconstruction of both ligament by using endo button thread system and its outcomes were assessed clinically and radiologically.Results: Patients were evaluated using American shoulder and elbow score (ASES) score and Constant shoulder score. Average ASES score was 90 (range 68.3-98.3) and constant score was 88 (range 63-96). According to constant score 7 patients had excellent outcome, 6 patients had good outcome, 2 patients had adequate outcome. All patients reported satisfaction with the treatment. The patients were followed upto 6 months.Conclusions: The technique proved to be effective in treating acute. Acromioclavicular joint dislocations (Rockwood type III-VI) with a high degree of patient satisfaction

Detection of field-free magnetization switching through thermoelectric effect in Ta/Pt/Co/Pt with significant spin-orbit torque and competing spin currents

Application of sufficient lateral current to a heavy metal (HM) can switch the perpendicular magnetization orientation of adjacent ferromagnetic layer (FM) through spin-orbit torques (SOTs). The choice of the HM and its arrangement plays a major role for the SOT induced magnetization switching in magnetic heterostructures. Here, in asymmetric Pt/Co/Pt heterostructures, anti-damping (AD) SOT prevails. Ta addition to this stack (Ta/Pt/Co/Pt) give rise to several compelling effects viz. competing spin currents (due to opposite spin-Hall angles of adjacent Ta and Pt layers), significant AD-SOT, thermoelectric effects (particularly, anomalous Nernst effect (ANE)), and enhanced perpendicular magnetic anisotropy. For this Ta/Pt/Co/Pt stack, the AD-SOT values are stabilized to that of the Pt/Co/Pt stack, which is significant than what is expected for a stack with competing spin currents. Current-induced field-free magnetization switching was absent in uniformly grown Ta/Pt/Co/Pt stack. It was observed that a thickness gradient is essential to assist the field-free magnetization switching in these heterostructures. Further, the thermoelectric effects are utilized to develop a technique to detect the field-free magnetization switching. This technique detects the second harmonic ANE signal as a reading mechanism. Using ANE symmetry with the applied current, the switching can be detected in a single current sweep which was corroborated to the conventional DC Hall method.Comment: v1; 32pp, 13 fig

Space-Time Code Design Using Quaternions, Octonions and Other Non-Associative Structures

There are several non-associative finite dimensional division algebras over different number fields. Their representations in the corresponding matrix algebras preserve additive structure. However, the embedding does not preserve multiplication as matrix multiplication is associative. As such, it gives a generalized matrix representation. Indeed, a non-associative structure provides different platforms for more effective and useful space-time coding satisfying rank criteria, and coding gain criteria for multiple antenna wireless communication. Associative division algebras have dimension restrictions, whereas non-associative division algebras over suitable fields exist in infinitely many dimensions. We illustrate the above program by using octonion algebras